Version 2.0.1 updates the 3D viewer to Mol* (Molstar), which provides faster WebGL2 rendering and smoother interaction on large and multi-chain structures. New in this release: per-residue effect prediction table (AlphaMissense, EVE, ESM-1b, FoldX, CADD, conservation via ProtVar), binding pocket analysis with PDBe-KB known sites and pocket confidence scoring, Open Targets drug tractability data, AlphaFill ligand transplant evidence, and Tanimoto ligand similarity. Export options now include PyMOL and VMD session scripts in addition to CSV. Performance on Firefox is improved by disabling expensive post-processing effects (MSAA, ambient occlusion, outline).

Major Features
Functional Features window
Family & Domains window
Stream structures: AlphaFold model loads instantly, full discovery (experimental/isoform/computed) streams behind it
Isoform AlphaFold models: now fully supported with correct annotation mapping
PyMOL/VMD session export: Download menu has two new options to export a self-contained script that reproduces the exact on-screen view, so you can continue working in those programs
Ligand similarity by CACTVS fingerprint: Tanimoto scoring against PubChem for finding similar ligands in the structure
UX & Fixes
Buttons are anchored to subheadings instead of the main heading.
minor bug fixes.