I'll find what I can do about this problem asap. I'm more familiar with Alt+F4 though.

Edit: I've changed the hotkey to "Ctrl+Shift+Q" ("Cmd+Shift+Q" for macOS), hope this brings you more convenient.

The hotkey shortcut have to be hard coded in manifest.json, it is the rule of webExtension so I think it'll not be easy to make an option to customize it. Chrome extension already have the built-in hotkey modifier (For example https://www.howtogeek.com/127162/how-to-create-custom-keyboard-shortcuts-for-browser-actions-and-extensions-in-google-chrome/) so we might have to wait for firefox to add this feature.

Sorry for the late reply. There are some limitation in webExtensions when compare to good old XUL addons, so some features like "hold ctrl or ctrl+shift to translate hovering word" are not possible right now (you can use Ctrl+Q to bring up the addon popup though).

If you want to translate some text in links, I have this little trick: hold your "alt" button when select some text inside a link, then you can choose that text without accidentally click to that link.

I know about the popup's results is probably looks too complicated, I'm still finding solutions for that. My extension uses wiktionary result in html format, while the 'Wiktionary and Google Translate' addon by Zen gets the wiktionary result in 'wiki markup' format, which is very hard to parse, and the addon won't show you the meaning of a word in verb, or noun, adj, adv,... and just show a few meanings of the word if I remembered right.

And I know little about javascript when I wrote this extension, but right now I've got a lot better so I may try to rewrite this extension when I have time.